FOR PATIENTS WHO HAVE SEEN EVERYONE ELSE

FOR PATIENTS WHO HAVE SEEN EVERYONE ELSE

When standard medicine stops looking for answers, we find the root cause.

When standard medicine stops looking for answers, we find the root cause.

When standard medicine stops looking for answers, we find the root cause.

Led by Dan Purser MD, the nation’s leading solo practitioner in complex inflammatory genetics. We utilize FDA-approved intracellular testing and advanced genetic curation to uncover the precise biological root of your chronic fatigue, brain fog, and neurological issues.

Led by Dan Purser MD, the nation’s leading solo practitioner in complex inflammatory genetics. We utilize FDA-approved intracellular testing and advanced genetic curation to uncover the precise biological root of your chronic fatigue, brain fog, and neurological issues.

Led by Dan Purser MD, the nation’s leading solo practitioner in complex inflammatory genetics. We utilize FDA-approved intracellular testing and advanced genetic curation to uncover the precise biological root of your chronic fatigue, brain fog, and neurological issues.

Apply for a Consultation

Apply for a Consultation

Limited availability for complex cases.

1,400+

1,400+

5-Star Reviews

The #1 rated solo MD in the USA

40+

40+

Published Books

Including Amazon best-sellers and medical textbooks

500

500

Medical Conferences

Addressed worldwide

10,000+

10,000+

Patients Helped Freely

End Fibromyalgia Initiative

Dr Purser personal statement image

Personal statement

Dr Purser personal statement image

Personal statement

DR. PURSER PERSONAL STATEMENT

DR. PURSER PERSONAL STATEMENT

Insatiably curious. Persistent. Root-cause focused.

Insatiably curious. Persistent. Root-cause focused.

Insatiably curious. Persistent. Root-cause focused.

Honestly, I was shocked when I was informed by our Google contacts that I was the top ranked — yes, #1 — solo MD in the USA. But it’s nothing special; just a popularity contest. The ranking is based on a mountain of 5-star reviews I didn’t even know I had. I’m not that smart — my youngest daughter teases me by calling me a “dumb Okie,” which I can certainly be some days — and I’m not board certified. Board certification was barely a thing, and not important was what we were told, when I came out of residency 40+ years ago. Plus, I was more interested in research and product design/development, which I’ve done a lot of. Back then, my role model was the billionaire Dr. Armand Hammer — who, yes, unknown to almost everybody, was an MD himself. So here I am… What makes me special, if anything does, is that, like Einstein famously said about himself — he didn’t know me — I am insatiably curious and persistent. I just never stop until I can figure out a patient and find the root cause of their issue. The root cause usually works best. I can and do prescribe pharmaceuticals occasionally and suggest them often, but I use them rarely when addressing the root cause works much better.

Honestly, I was shocked when I was informed by our Google contacts that I was the top ranked — yes, #1 — solo MD in the USA. But it’s nothing special; just a popularity contest. The ranking is based on a mountain of 5-star reviews I didn’t even know I had. I’m not that smart — my youngest daughter teases me by calling me a “dumb Okie,” which I can certainly be some days — and I’m not board certified. Board certification was barely a thing, and not important was what we were told, when I came out of residency 40+ years ago. Plus, I was more interested in research and product design/development, which I’ve done a lot of. Back then, my role model was the billionaire Dr. Armand Hammer — who, yes, unknown to almost everybody, was an MD himself. So here I am… What makes me special, if anything does, is that, like Einstein famously said about himself — he didn’t know me — I am insatiably curious and persistent. I just never stop until I can figure out a patient and find the root cause of their issue. The root cause usually works best. I can and do prescribe pharmaceuticals occasionally and suggest them often, but I use them rarely when addressing the root cause works much better.

Honestly, I was shocked when I was informed by our Google contacts that I was the top ranked — yes, #1 — solo MD in the USA. But it’s nothing special; just a popularity contest. The ranking is based on a mountain of 5-star reviews I didn’t even know I had. I’m not that smart — my youngest daughter teases me by calling me a “dumb Okie,” which I can certainly be some days — and I’m not board certified. Board certification was barely a thing, and not important was what we were told, when I came out of residency 40+ years ago. Plus, I was more interested in research and product design/development, which I’ve done a lot of. Back then, my role model was the billionaire Dr. Armand Hammer — who, yes, unknown to almost everybody, was an MD himself. So here I am… What makes me special, if anything does, is that, like Einstein famously said about himself — he didn’t know me — I am insatiably curious and persistent. I just never stop until I can figure out a patient and find the root cause of their issue. The root cause usually works best. I can and do prescribe pharmaceuticals occasionally and suggest them often, but I use them rarely when addressing the root cause works much better.

Read My Reviews

Read My Reviews

“Your labs are normal.” But you still feel exhausted, foggy, and in pain.

“Your labs are normal.” But you still feel exhausted, foggy, and in pain.

“Your labs are normal.” But you still feel exhausted, foggy, and in pain.

Most medical practices test your blood surface-level and stop searching when the standard charts look clear. We specialize in the cases that defy traditional definitions.

Most medical practices test your blood surface-level and stop searching when the standard charts look clear. We specialize in the cases that defy traditional definitions.

Most medical practices test your blood surface-level and stop searching when the standard charts look clear. We specialize in the cases that defy traditional definitions.

If you are battling unexplained:

Chronic, systemic inflammation and muscular pain

Chronic, systemic inflammation and muscular pain

Debilitating fatigue and physical exhaustion

Debilitating fatigue and physical exhaustion

Unresolved brain fog, memory issues, or neurological anomalies

Unresolved brain fog, memory issues, or neurological anomalies

You don’t need another faceless, generic prescription. You need a deep-layer diagnosis and detailed report.

You don’t need another faceless, generic prescription. You need a deep-layer diagnosis and detailed report.

You don’t need another faceless, generic prescription. You need a deep-layer diagnosis and detailed report.

The Science: How Dr. Purser uncovers the answer

The Science: How Dr. Purser uncovers the answer

The Science: How Dr. Purser uncovers the answer

FDA-Approved Intracellular Testing

FDA-Approved Intracellular Testing

Standard blood work only tells us what is floating around your cells. Our advanced testing looks inside the cell walls to measure absolute mineral, vitamin, and amino acid deficiencies that dictate your daily cellular energy.

Standard blood work only tells us what is floating around your cells. Our advanced testing looks inside the cell walls to measure absolute mineral, vitamin, and amino acid deficiencies that dictate your daily cellular energy.

Advanced Curated Genetic Testing

Advanced Curated Genetic Testing

Dr. Purser leads one of the largest inflammatory genetics counseling practices in the country. We analyze your unique DNA markers to identify the exact genetic switches causing chronic, unprompted inflammatory loops.

Dr. Purser leads one of the largest inflammatory genetics counseling practices in the country. We analyze your unique DNA markers to identify the exact genetic switches causing chronic, unprompted inflammatory loops.

WHAT DR. PURSER DOES WHEN SOMETHING DOESN’T ADD UP

WHAT DR. PURSER DOES WHEN SOMETHING DOESN’T ADD UP

I research everything when I suspect a problem.

I research everything when I suspect a problem.

I research everything when I suspect a problem.

These are just some of the articles, pathway diagrams, and patient writeups I’ve done while working through complex cases. I rarely give up until I can help a patient find the root-cause answer — and the relief they deserve.

These are just some of the articles, pathway diagrams, and patient writeups I’ve done while working through complex cases. I rarely give up until I can help a patient find the root-cause answer — and the relief they deserve.

These are just some of the articles, pathway diagrams, and patient writeups I’ve done while working through complex cases. I rarely give up until I can help a patient find the root-cause answer — and the relief they deserve.

POTENTIAL PATIENTS — Read the MTHFR + PEMT + Homocysteine Guide

POTENTIAL PATIENTS — Read the MTHFR + PEMT + Homocysteine Guide

POTENTIAL PATIENTS — Read the MTHFR + PEMT + Homocysteine Guide

Read My Reviews

Read My Reviews

“A popular restaurant might easily get 1,400 reviews. For a solo medical doctor handling complex, life-altering chronic cases, it is virtually unheard of. It represents 1,400 lives given their answers back.”

“A popular restaurant might easily get 1,400 reviews. For a solo medical doctor handling complex, life-altering chronic cases, it is virtually unheard of. It represents 1,400 lives given their answers back.”

“A popular restaurant might easily get 1,400 reviews. For a solo medical doctor handling complex, life-altering chronic cases, it is virtually unheard of. It represents 1,400 lives given their answers back.”

Watch Dr. Purser’s Educational YouTube Library

Hundreds of videos

Cytokine and genetic causes diagram
Cytokine and genetic causes diagram

What Dr. Purser Sees, Does, and Writes Almost Every Day

What Dr. Purser Sees, Does, and Writes Almost Every Day

Honestly, I was shocked when I was informed by our Google contacts that I was the top ranked (yes, #1 !!?) solo MD in the USA. But it’s nothing special — just a popularity contest. The ranking is just based on a mountain of 5 star reviews I didn’t even know I had. I’m not that smart (my youngest daughter teases me by calling me a “dumb Okie”, which I can certainly be some days), and not board certified (board certification was barely a thing AND not important was what we were told, when I came out of residency 40+ years ago), plus I was more interested in research, and product design/development (which I’ve done a lot of…). Back then my my role model was the billionaire Dr Armand Hammer — who yes, unknown to almost everybody, was a MD himself (ask Gemini — shocking I KNOW…). So here I am…


What makes me special (if anything does) because I’m really not that bright, is that, like Einstein famously said (about himself — he didn’t know me), I am insatiably curious — and persistent — just never stopping until I can figure out a patient and find the root cause to dealing with their issue(s) — the root cause just works the best usually. I can and do prescribe pharmaceuticals occasionally and suggest them often, but use them rarely when addressing the root cause usually works much better.

Does your current doctor do this? Homocysteine, cytokines, genetics, and root-cause inflammatory pattern analysis.

Does your current doctor do this? Homocysteine, cytokines, genetics, and root-cause inflammatory pattern analysis.

FIBROMYALGIA RESEARCH · A SEARCH FOR A CURE

End Fibromyalgia with Natural Options

End Fibromyalgia with Natural Options

End Fibromyalgia with Natural Options

Dr. Purser’s Facebook research community, END FIBROMYALGIA WITH NATURAL OPTIONS, has helped more than 10,000 sufferers explore root-cause therapies. The reviews below are anonymized public comments from 2023, shared as patient-reported outcomes from people trying the protocol.

Dr. Purser’s Facebook research community, END FIBROMYALGIA WITH NATURAL OPTIONS, has helped more than 10,000 sufferers explore root-cause therapies. The reviews below are anonymized public comments from 2023, shared as patient-reported outcomes from people trying the protocol.

Dr. Purser’s Facebook research community, END FIBROMYALGIA WITH NATURAL OPTIONS, has helped more than 10,000 sufferers explore root-cause therapies. The reviews below are anonymized public comments from 2023, shared as patient-reported outcomes from people trying the protocol.

10,000+

Sufferers in the research community

Copper + MTHFR

Patient-reported therapy themes

2023

Public review excerpts, names removed

2023 REVIEW EXCERPT

“It took a couple months for me. I didn’t think it was even working. Adding copper balance in on month 2 was very helpful. I am 3 years low copper and never looking back.”

2023 REVIEW EXCERPT

“It’s different for everyone. It took me longer than most because I had been eating super high copper foods most of my life. For me the major improvement was about 90 days in.”

2023 REVIEW EXCERPT

“I started feeling noticeably better in a week. It took a while to get everything dialed in, but I went from constant level 8 pain to a super manageable 0–2 pain with no prescription pain medications within about four months.”

2023 REVIEW EXCERPT

“I started feeling the difference in a week. Each time I gave up a high copper food I noticed I was eating a lot of copper and even had it in several of my supplements. Some things took longer to get better, but the changes have made a huge difference.”

2023 REVIEW EXCERPT

“In 2019 I got an unknown respiratory virus while travelling and the fibromyalgia symptoms shot up to a 9–10. There were many days I couldn’t get out of bed. I began looking for solutions.”

2023 REVIEW EXCERPT

“I heard Dr. Purser speak at a conference and was impressed with his knowledge. I tested the low copper diet and supplements recommended for me. After about 90 days on the protocol, my symptoms began to improve.”

Anonymized 2023 public review excerpts from End Fibromyalgia with Natural Options
Anonymized 2023 public review excerpts from End Fibromyalgia with Natural Options

More reviews have been added since 2023

More reviews have been added since 2023

The Facebook page began as a practical research community for people suffering with fibromyalgia who were willing to test root-cause, nutritional, and genetic-inflammatory ideas. This section preserves the 2023 public review snapshot while pointing visitors toward the larger ongoing community.

Visit END FIBROMYALGIA WITH NATURAL OPTIONS

Visit END FIBROMYALGIA WITH NATURAL OPTIONS

Homocysteine, cytokines, and the inflammatory switchboard

Homocysteine, cytokines, and the inflammatory switchboard

Homocysteine, cytokines, and the inflammatory switchboard

A working visual library of the pathways Dr. Purser reviews when connecting homocysteine, NF-κB, NRF2, TNF-alpha, cytokines, oxidative stress, and tissue-level damage.

A working visual library of the pathways Dr. Purser reviews when connecting homocysteine, NF-κB, NRF2, TNF-alpha, cytokines, oxidative stress, and tissue-level damage.

A working visual library of the pathways Dr. Purser reviews when connecting homocysteine, NF-κB, NRF2, TNF-alpha, cytokines, oxidative stress, and tissue-level damage.

Alpha-Gal Syndrome and Potential Cytokines report preview
Alpha-Gal Syndrome and Potential Cytokines report preview

Article

Alpha-Gal Syndrome & Potential Cytokines: Report

Alpha-Gal Syndrome & Potential Cytokines: Report

A cytokine-focused clinical note connecting Alpha-Gal syndrome, Th2 immune response, IL-4, IL-5, IL-13, mast-cell activation, and inflammatory pattern interpretation.

CIRS clinical research report preview
CIRS clinical research report preview

Article

CIRS Clinical Research Report: The Transsulfuration-Cytokine Axis

CIRS Clinical Research Report: The Transsulfuration-Cytokine Axis

A mechanistic review of hyperhomocysteinemia, glutathione depletion, genomic upregulation, IL-8, MCP-1, and NF-κB patterns in biotoxin illness.

Browse Dr. Purser’s 40+ publications

On Amazon

CREST Syndrome article preview
CREST Syndrome article preview

Article

CREST Syndrome

CREST Syndrome

A cytokine-centered writeup on CREST syndrome, Th2 immune patterns, fibrosis signaling, IL-4, IL-6, IL-8, IL-13, TGF-β, and tissue-level inflammatory damage.

Cytokine causes of ulcerative colitis article preview
Cytokine causes of ulcerative colitis article preview

Article

Cytokine Causes of Ulcerative Colitis

Cytokine Causes of Ulcerative Colitis

A patient-facing writeup connecting ulcerative colitis to inflammatory cytokines, TNF-α, IL-1β, IL-8, Th17 activity, and biologic response patterns.

IL-8 homocysteine signs symptoms associated diseases report preview
IL-8 homocysteine signs symptoms associated diseases report preview

Article

IL-8 Homocysteine: Signs, Symptoms, Associated Diseases

IL-8 Homocysteine: Signs, Symptoms, Associated Diseases

A report on IL-8 in the context of homozygous MTHFR risk, neutrophil trafficking, respiratory symptoms, vascular inflammation, pain, and autoimmunity.

IL23R report preview
IL23R report preview

Article

IL23R Report

IL23R Report

A clinical note on IL23R dysregulation, inflammatory bowel disease, immune-cell ignition, Th17 signaling, mucosal damage, and ulcerative colitis pathogenesis.

Lichen planus and cytokines report preview
Lichen planus and cytokines report preview

Article

Lichen Planus and Cytokines

Lichen Planus and Cytokines

A report explaining cytokine-driven immune activation in lichen planus, T-cell recruitment, keratinocyte attack, TNF-alpha, IL-1, IL-6, IL-8, Th1, Th17, IL-23, and IL-17 signaling.

NF-kB pathway cellular master switch for inflammation
NF-kB pathway cellular master switch for inflammation

NF-κB pathway: cellular master switch for inflammation

NRF2 pathway overview diagram
NRF2 pathway overview diagram

NRF2 antioxidant response pathway

NRF2 best pathway diagram
NRF2 best pathway diagram

NRF2 activation and oxidative stress control

Homocysteine-induced IL-8 and MCP-1 release from monocytes
Homocysteine-induced IL-8 and MCP-1 release from monocytes

Homocysteine-induced IL-8 and MCP-1 release

IL-8 and MCP-1 mediated attack on arterial wall
IL-8 and MCP-1 mediated attack on arterial wall

IL-8 and MCP-1 attack on the arterial wall

IL-8 and MCP-1 mediated renal cell attack and damage
IL-8 and MCP-1 mediated renal cell attack and damage

IL-8 and MCP-1 renal cell attack and damage

Breaking the siege via the antioxidant triad SOD catalase GSH
Breaking the siege via the antioxidant triad SOD catalase GSH

Breaking the siege with SOD, catalase, and GSH

TNF-alpha firestorm diagram
TNF-alpha firestorm diagram

TNF-alpha firestorm

TNF-alpha complications diagram
TNF-alpha complications diagram

TNF-alpha complications map

TNF-alpha treatment options diagram
TNF-alpha treatment options diagram

TNF-alpha treatment options

Stop managing symptoms. Find your root cause.

Stop managing symptoms. Find your root cause.

Stop managing symptoms. Find your root cause.

Dr. Dan Purser MD operates a highly exclusive solo practice dedicated strictly to complex diagnostic puzzles. Spaces are heavily limited to ensure unmatched analytical depth for every case.

Dr. Dan Purser MD operates a highly exclusive solo practice dedicated strictly to complex diagnostic puzzles. Spaces are heavily limited to ensure unmatched analytical depth for every case.

Dr. Dan Purser MD operates a highly exclusive solo practice dedicated strictly to complex diagnostic puzzles. Spaces are heavily limited to ensure unmatched analytical depth for every case.

Submit Your Case for Review

Submit Your Case for Review

Book an appointment or talk to a real live medical secretary.

Book an appointment or talk to a real live medical secretary.

Call the office to discuss your issues and find out whether your case may be a fit.

Call the office to discuss your issues and find out whether your case may be a fit.

Call 801.796.7667

Call 801.796.7667

Limited availability • Complex cases only

Create a free website with Framer, the website builder loved by startups, designers and agencies.